Preheat your oven to 375°F (190°C).
In a small bowl, mix together the olive oil, garlic powder, cumin, chili powder, salt, and pepper.
Rub the spice mixture evenly over both chicken breasts.
Place the seasoned chicken breasts in a baking dish and bake for 25-30 minutes, or until the internal temperature reaches 165°F (75°C).
Remove the chicken from the oven and top each breast with fresh salsa and shredded cheese.
Return the dish to the oven and bake for an additional 5-7 minutes, until the cheese is melted and bubbly.
Remove from the oven and let rest for a few minutes. Top with diced avocado and chopped cilantro before serving.
Serve with lime wedges on the side.