Preheat your oven to 400°F (200°C). Line a large sheet pan with parchment paper for easy cleanup.
In a small bowl, whisk together the Dijon mustard, honey, chili powder, garlic powder, onion powder, and olive oil until well combined.
Place the salmon fillets on one side of the prepared sheet pan. Brush the chili Dijon mixture evenly over the top of the salmon.
In a separate bowl, toss the broccoli, baby carrots, and bell peppers with a drizzle of olive oil, salt, and pepper until well coated. Spread the vegetables on the other side of the sheet pan.
Bake in the preheated oven for 15-20 minutes, or until the salmon flakes easily with a fork and the vegetables are tender.
Remove from the oven and let cool for a couple of minutes. Serve with lemon wedges on the side for an extra burst of flavor.